Topic · Pathology and Forensic Medicine · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
4 papers
Kyle Yuan, Phillip Truong, Charkira Patrick…·Collynn F. Woeller
This study identifies sorafenib as a potential therapeutic for thyroid eye disease by analyzing transcriptomic changes in orbital fibroblasts and validating its effects on key pathways.
Yanchen Zhang, Ende Wu, Weibin Liu…·Wencan Wu
This study develops YC3, a TSHR-targeting aptamer that inhibits TSHR signaling and treats Graves' ophthalmopathy by binding to a novel allosteric site.
Dong Won Kim, Soo-Hyun Kim, Jeong Soon Han…·Fatemeh Rajaii
This study uses single nucleus RNA-Seq to show increased adipogenesis and IGF-1R pathway alterations in TED orbital fat, suggesting linsitinib as a potential therapeutic.
Mythri Pullela, Mehmet N. Ağaoğlu, Anand C. Joshi…·Vallabh E. Das
This study examines neural and muscle plasticity in monkeys after strabismus surgery, showing initial neuronal changes that reduce treatment effectiveness but resolve over time, while peripheral muscle adaptations persist.