Kawasaki Disease and Coronary Complications

The paper compares plasma cell-free RNA and protein levels in children with inflammatory diseases, finding minimal correlation but similar diagnostic utility for distinguishing Kawasaki Disease from MIS-C.

This study uses single-cell RNA sequencing to identify dysregulated signaling molecules in Kawasaki Disease patients with and without coronary artery lesions.

This study shows that gut microbiota depletion reduces cardiovascular inflammation in a mouse model of Kawasaki disease, and specific bacteria or their metabolites can alleviate vasculitis by improving gut barrier function.

This study identifies dysregulated antibody-mediated cellular responses in MIS-C, linking NK cell dysfunction to immune pathology and suggesting potential therapeutic interventions.

This study identifies rare genetic variants in MIS-C patients from the Middle East, linking them to disease onset and treatment resistance.

This study stratifies Kawasaki Disease patients using transcriptomic and proteomic profiles, finding KD responses resemble bacterial infections but with distinct features suggesting alternative triggers.