Topic · Oncology · Medicine

PARP inhibition in cancer therapy

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Biochemistry·bioRxivPreprint·Jul 20, 2026
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MicroRNA spatial profiling for assessing drug efficacy in BRCA1-related triple-negative breast tumors
Omar N. Mohd, Lin Wang, Barbara Sardella…+4 more authors·Patrick S. Doyle
Latent Dirichlet allocation topics from hydrogel-array spatial miRNA maps of day-10 treated K14-Cre Brca1/Trp53 mouse breast tumors separated olaparib-sensitive (miR-21-dominated) from resistant (let-7a-dominated) tumors.
DOI 10.64898/2026.01.12.698824
mouse·spatial transcriptomics
·𝕏 Post·Bluesky