Topic · Plant Science · Agricultural and Biological Sciences

Natural Compound Pharmacology Studies

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

Cancer Biology·PLoS ONEPeer-reviewed·Apr 3, 2025
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Elucidating the Impact of Hypericum alpestre Extract and L-NAME on the PI3K/Akt Signaling Pathway in A549 Lung Adenocarcinoma Cells
Hayarpi Javrushyan, Mikayel M․ Ginovyan, Gayane Petrosyan…+5 more authors·Nikolay V. Avtandilyan
This study investigates how Hypericum alpestre extract and L-NAME affect the PI3K/Akt signaling pathway in A549 cells, showing enhanced apoptosis and inhibition of TNFα/COX-2 and VEGFα/MMP-2 pathways.
15 citationstop 2%
human·bulk RNA-seq
·𝕏 Post·Bluesky
Cancer Biology·Journal of Food BiochemistryPeer-reviewed·Jan 1, 2025
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Garcinone C suppressed the proliferation of gastric cancer cells through regulating Hedgehog signaling
Yimeng Zhou, Jin Tae Kim, Jung Won Kwon…+4 more authors·Hong Jin Lee
This study shows garcinone C inhibits gastric cancer cell proliferation by suppressing Hedgehog signaling through Gli1/2 downregulation and nuclear translocation blockage.
1 citation
human·proteomics
·𝕏 Post·Bluesky