Glutathione Transferases and Polymorphisms

This study finds that the GSTT1-absent genotype is significantly associated with increased breast cancer risk and poorer overall survival in Pakistani patients.

This study investigates the response of the soluble GST superfamily in Fasciola hepatica to TCBZ-SO exposure, identifying specific GST isoforms involved in detoxification.

This study identifies Gstp proteins' role in neurite initiation and elongation during cortical development, showing their regulation through JNK signaling.

This study investigates the association between GSTM1 copy number and kidney failure risk in a large cohort, finding no significant association after adjustments.

The paper investigates the evolutionary history of the GSTM1 gene deletion in East Asian populations, finding evidence of a soft sweep and its association with disease susceptibility.