Topic · Oncology · Medicine

Vascular Tumors and Angiosarcomas

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

Cancer Biology·bioRxivPreprint·Oct 9, 2026
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MYC drives endothelial transformation and dedifferentiation in angiosarcoma
Chen Khuan Wong, Dan Li, Tomer Itkin…+18 more authors·Yu Chen
This study shows MYC drives endothelial transformation and dedifferentiation in angiosarcoma by promoting lineage plasticity and cell growth.
DOI 10.64898/2026.10.07.757149
mouse·ATAC-seq
·𝕏 Post·Bluesky
Cancer Biology·bioRxivPreprint·May 17, 2026
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Subclonal IDH1/2 Mutations as a Targetable Vulnerability in Vascular Tumors
Dong-Min Yu, E L Lee, Gabriel J. Starrett…+15 more authors·Richard C Wang
This study identifies low-variant allele frequency IDH1/2 mutations in sporadic angiosarcoma and shows they drive tumorigenesis through non-cell-autonomous mechanisms, responding to ivosidenib treatment.
DOI 10.64898/2026.05.14.725132
human·DNA methylation
·𝕏 Post·Bluesky