Dietary Effects on Health

This study shows intermittent fasting changes chromatin accessibility and gene expression in brain and muscle tissues of mice, affecting metabolic and functional pathways.

This study shows that parental time-restricted feeding affects offspring metabolic traits differently in males and females, offering protection against diet-induced metabolic issues.

This study shows chronic intermittent fasting impairs β-cell maturation and function in adolescent mice, but not in adults, with similar patterns observed in human type 1 diabetes.

This study assesses the effects of fasting-mimicking diets on salivary metabolites, weight loss, and biomarkers in humans, finding significant changes in energy metabolism and gut microbiome metabolites.

The paper shows that repeated fasting events sensitize enhancers and gene expression to enhance ketogenesis in mice.

This study shows that time-restricted feeding improves memory and metabolic health in mice on an obesogenic diet by restoring thyroid hormone signaling in the hippocampus.

This study examines how fasting affects response inhibition to food-related cues, finding increased commission errors in high-caloric food trials during fasting.

This study investigates whether fasting after ischemic stroke reduces infarct volume and inflammation in rats.

Time-restricted feeding reduces amyloid deposition, improves behavior, and normalizes gene expression in a mouse model of Alzheimer's disease.

The paper introduces a digital twin model that predicts diet response and metabolic changes before and after fasting by integrating clinical data and mechanistic models.

This study shows that intermittent fasting enhances hippocampal Npy expression and promotes neurogenesis after traumatic brain injury, improving cognitive performance.

This study examines how caloric restriction and intermittent fasting interact with genetics to influence physiological health in mice, finding diet-specific effects and significant genetic contributions to multiple traits.

This study uses multi-omics analyses to investigate how different intermittent fasting regimens affect heart function and molecular pathways in mice.

The paper examines gene expression changes across multiple organs during short-term fasting in mice, identifying a brain-liver-fats network with significant immune system regulation.

This study shows intermittent fasting modulates H3K9me3 epigenetic marks and transcriptomic changes in mouse cerebellum, with lasting effects after refeeding.

This study shows that time-restricted feeding improves biconditional associative learning in aged rats, regardless of diet type, suggesting potential benefits for cognitive health.