Topic · Developmental Neuroscience · Neuroscience

Anesthesia and Neurotoxicity Research

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

Neuroscience·PLoS BiologyPeer-reviewed·Aug 21, 2019
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Astroglial dysfunctions drive aberrant synaptogenesis in developing brain with lengthy general anesthesia
Bin Zhou, Lingmin Chen, Ping Sung Liao…+10 more authors·Ruotian Jiang
This study shows that sevoflurane exposure disrupts astrocyte function, leading to synaptic overgrowth and dysfunction in developing brains.
91 citations
mouse·experimental assay
·𝕏 Post·Bluesky
Neuroscience·bioRxivPreprint·Dec 6, 2018
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Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunction
Jiang Zhong, Wei Xu
This study investigates the impact of sevoflurane on DNA hydroxymethylation and Uhrf2 levels in the hippocampus and amygdaloid nucleus of elderly mice with postoperative cognitive dysfunction.
2 citations
mouse·DNA methylation
·𝕏 Post·Bluesky