Central nervous system-derived inflammasome cytokines drive neuroglial injury and cerebral oedema in viral encephalitis, despite corticosteroid therapy
Franklyn Nkongho Egbe, Cordelia Dunai, Claire Hetherington…·Benedict Daniel Michael
This study identifies IL-1 and IL-6 as key drivers of neuroinflammation in HSV encephalitis, showing they are not reduced by corticosteroids and are associated with poor outcomes.