Tardigrade Biology and Ecology

This study shows that tardigrades undergo storage cell proliferation during growth, challenging the eutelic hypothesis and linking DNA replication to molting and survival.

This study analyzes the transcriptome of Hypsibius exemplaris exposed to bleomycin, identifying tardigrade-specific gene families and tryptophan metabolism pathway enrichment linked to stress tolerance.

The paper identifies a novel tardigrade-specific DNA binding protein, TDR1, that enhances resistance to ionizing radiation in human cells.

This study examines the nervous system organisation and morphological changes in encysted Thulinius ruffoi tardigrades over 11 months.

Tardigrades upregulate DNA repair genes after ionizing radiation, enhancing their radiation tolerance.

This study compares the transcriptomic responses of bdelloid rotifers to desiccation and ionizing radiation, finding shared and distinct molecular mechanisms.

This study identifies the embryonic origin of primordial germ cells in the tardigrade Hypsibius exemplaris using molecular markers and lineage tracing.

The paper develops a genetic tool for tardigrades to study anhydrobiosis by enabling live imaging of protein dynamics.

This study identifies intrinsically disordered proteins in tardigrades using a support vector machine, highlighting 82 potential TDPs for further research on cryptobiosis mechanisms.

The paper identifies a new nematode species from Siberian permafrost and shows it shares cryptobiosis mechanisms with C. elegans dauer larvae.

This study investigates the role of LEA-1 protein in desiccation tolerance in C. elegans, showing its protective effects against multiple stresses and identifying functional motifs that can be applied across species.

The paper uses genome editing to show that calcium signaling pathways, specifically calmodulin-calcineurin-NFAT and calmodulin-calmodulin kinase-CREB, play distinct roles in anhydrobiosis in Pv11 cells.

This study uses the tardigrade Hypsibius exemplaris to investigate mitochondrial alternative oxidase (AOX) activity and its role in animal physiology.

This study demonstrates that tardigrade intrinsically disordered proteins can protect engineered bacteria during lyophilization, enabling room-temperature storage with high survival rates.

This study identifies a novel Mn-dependent peroxidase involved in tardigrade anhydrobiosis through transcriptomic and crystallographic analyses.

This study identifies novel anhydrobiosis-related proteins in the heterotardigrade Echiniscus testudo, showing structural changes similar to eutardigrades but lacking sequence conservation, suggesting convergent evolution.

This study shows that dehydrated C. elegans stocks can survive multiple freeze-thaw cycles using trehalose or glycerol.

The paper analyzes LEA protein expression and localization in anhydrobiotic midge cells to understand their role in desiccation tolerance.

This study uses CAGE-seq to analyze transcriptome changes in Pv11 cells during desiccation and rehydration, identifying DEGs and suggesting DNA repair as a recovery mechanism.

The paper compares the genomes of two tardigrade species to investigate their evolutionary relationships and mechanisms of extreme survival.