Medical and Biological Sciences

This paper introduces a modified Golgi staining protocol for mouse cortical tissue that improves workflow efficiency and consistency for neuronal morphology visualization.

The paper demonstrates predictable Golgi-Cox staining patterns in mouse brains influenced by neuronal maturity, time-of-day, and environmental stimuli.

The paper examines how prolonged post-fixation affects immunohistochemical and histochemical staining in postmortem human brains, finding mixed correlations with staining intensity and limited effects of age and PMI.

The paper compares histological quality and antigenicity preservation in human brains fixed with different solutions, finding that AFS-fixed brains show better antigen labeling and tissue quality than NBF or SSS.

This study compares fixative solutions used in human gross anatomy labs to preserve brain tissue antigenicity in mice, finding that two solutions maintain sufficient antigenicity for immunohistochemistry.