Medicinal Plant Research

This study identifies Khaya grandifoliola hydro-ethanolic extract as a potent inhibitor of HEV-PLpro protease, with anti-HEV activity comparable to ribavirin and no cytotoxicity.

This study evaluates the antiproliferative effects of Maerua edulis extracts on HeLa cells, identifies key phytochemicals, and shows their impact on gene expression related to apoptosis and cell cycle regulation.

This study screens historical plant recipes for antiviral activity against SARS-CoV-2, identifying four plant extracts with significant antiviral effects.

This study evaluates the anti-cancer effects of Vernolac extract on NTERA-2 cl.D1 cancer stem-like cells, showing significant cytotoxicity and apoptosis induction with minimal impact on non-cancerous cells.

This study profiles the chemical and bioactive compounds in different parts of Desmodium gangeticum and finds leaves contain more bioactive compounds than roots, suggesting leaves as a sustainable alternative for medicinal use.

This study evaluates the antioxidant, thrombolytic, analgesic, and antidiarrheal effects of a methanolic extract from Litsea monopetala leaves in animal models.

This study evaluates the analgesic, antipyretic, and antibacterial properties of Litsea glutinosa leaf extracts using in vivo and in vitro methods, finding significant pain inhibition and bacterial growth suppression.

This study evaluates the antiviral activity of Glycyrrhiza glabra root extracts against all four dengue serotypes in Vero cells, finding 98-100% inhibition at the maximum nontoxic dose with good selectivity.

This study evaluates the uterotonic activity of a methanol root extract from Azanza garckeana on isolated rat uterine smooth muscles, identifying a glycoside-related compound as the active constituent.

This study shows that the methanolic extract of Ruellia tuberosa L. flower induces ROS, causes G0/G1 cell cycle arrest, and promotes apoptosis in TNBC cells without toxicity in mice.

The paper identifies potential anti-SARS-CoV-2 compounds from Cissampelos pareira L. using connectivity map analysis and in vitro testing, showing high inhibition of viral replication.

This study shows that aqueous and ethanolic Epilobium parviflorum extracts reduce HT-29 colon cancer cell viability and induce apoptosis without significantly affecting non-cancerous BJ cells.