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The paper adapts an MS2-MCP system to visualize endogenous cytoplasmic mRNA in C. elegans embryos without affecting mRNA stability.

The paper investigates the evolutionary retention of ribosomal protein paralogs eS27 and eS27L by showing their subfunctionalized expression patterns are necessary for maintaining total protein expression across cell types.

This paper develops a hybrid RNA FISH and immunofluorescence protocol to visualize protein-DNA interactions on Drosophila polytene chromosomes, demonstrating its ability to detect protein localization to transgenes.

This study identifies conditionally essential genes in Zymomonas mobilis for aerobic and anaerobic growth using CRISPRi-seq, revealing roles of DNA repair and respiratory complexes in energy coupling and isoprenoid biosynthesis.

The paper shows that GCDCA and ceramide reduce the antiviral effect of 25-HC against norovirus in HIE, with 25-HC suppressing viral replication and altering gene expression related to cholesterol and interferon pathways.

This study identifies genetic loci associated with age at diagnosis of T2D in South Indian and European populations, revealing shared and distinct genetic architectures.

The paper analyzes whole-genome sequencing data from Cas9-edited mice to assess off-target mutagenesis, finding minimal off-target activity across 163 guide RNAs.

The paper examines the relationship between early life alcohol consumption and neuron-enriched exosomal miRNA expression, finding significant associations with specific miRNAs and biological functions.

The paper investigates genetic contributions to skin color variation in a Caribbean population with Native American, African, and European ancestry, identifying specific alleles and ancestry effects on pigmentation.

This study investigates the role of CHPF in ccRCC, finding it promotes proliferation and invasion, suggesting it as a prognostic marker and therapeutic target.

The paper identifies a two-locus genetic model for the loss of self-incompatibility in Arabidopsis lyrata through intercrossing populations and analyzing progeny breeding systems.

This study uses chloroplast and nuclear genomes to trace the evolutionary history of common beans, supporting a Mesoamerican origin and rejecting a new species classification.

This study shows that LIN-35 is required in both germline and soma to maintain fertility in C. elegans under moderate temperature stress.

This paper introduces MAS-ISO-seq, a method to boost throughput of long-read RNA sequencing for isoform discovery, showing improved detection of differentially spliced genes and cell clustering in T cells.

The paper identifies candidate genes with large fitness effects in aneuploid yeast under specific stress conditions using a piecewise constant model.

The paper estimates variance components, characterizes phenotypes, and evaluates genetic factors associated with bovine congestive heart failure in commercial feeder cattle.

The paper uses multimodal single-cell sequencing to show non-random distribution of a pathogenic mtDNA variant in retinal cells of a MELAS patient.

The paper develops a portable DNA barcoding method using deep learning to identify shark and ray species in trade, achieving 79.41% accuracy for 28 species.

The paper investigates genetic variation in recombination rates and distribution in Atlantic Salmon, finding sex-specific heritability and genetic independence between male and female crossover patterns.