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This study examines how the In(2L)t inversion in Drosophila melanogaster affects environmentally sensitive behaviors, showing sex-specific and temperature-consistent impacts on activity, foraging, and startle response.

This paper introduces a method to approximate LD matrices with sparse, banded matrices that are positive semi-definite, improving accuracy over existing methods on large genomic data.

The paper identifies a structural variation in lhcb6 in maize landraces that affects photosystem II maximum quantum efficiency through differential accumulation of LHCII antenna components.

The paper describes an aneuploid Arabidopsis mutant generated by ion beam mutagenesis, showing phenotypic variations and identifying candidate causal genes through transcriptome analysis.

The paper identifies pre-rRNA as a target of Dicer in quiescence and shows RiboCop silences rDNA through histone methylation.

The paper measures the functional impact of over two thousand SOD1 missense variants using saturation mutagenesis and cell-based assays, reclassifying 41% of previously uncertain variants as pathogenic.

The paper identifies a 138-gene transcriptional signature in gastric cancer peritumoral tissue that is conserved in tumors and associated with poor prognosis.

The paper investigates a human-specific VNTR in CACNA1C and shows it modulates neuronal calcium responses and transcription programs.

The paper investigates gene expression patterns caused by transcription factors (TFs) that rescue or fail to rescue specific phenotypes in Drosophila, finding constrained gene regulation despite weak correlation between TFs.

This study identifies BP-modulated genes in retinal tissues linked to EMAP and neurodegeneration, highlighting inflammation and oxidative stress pathways.

The paper examines behavioral variation in cocaine self-administration across multiple phases in genetically diverse mouse populations, identifying strain and sex differences and extreme strains for drug intake traits.

The paper establishes a framework to assess NALCN variant pathogenicity using functional and computational methods, distinguishing benign from gain- and loss-of-function variants.

The paper investigates the genetic structure of the Primula auricula complex across the Alps, highlighting the role of peripheral regions in shaping its phylogeography.

The paper shows that endogenous viral elements in brown algae can reactivate, replicate, and transmit viruses, challenging the view of EVEs as inert.

The paper introduces MoEPRS, a Mixture-of-Experts framework for personalized polygenic risk prediction, showing modest accuracy improvements over single-source models across diverse biobanks.

The paper presents a genomic breeding strategy using large-scale recombinant populations and prediction models to rapidly develop rice cultivars with desired traits.

The paper identifies new protein interactions of FANCA, revealing its roles in mRNA processes beyond DNA repair, and suggests potential therapeutic targets for Fanconi anemia.

This study analyzes the expression of C-MYC and its associated pathways in gastric adenocarcinoma, identifying dysregulated genes and their correlation with clinicopathological factors.

The paper introduces a Bayesian method for differential analysis of omics data that incorporates prior knowledge across platforms or species, improving robustness and generalizability.