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The paper compares five algorithms for deriving structural covariance networks in the thalamocortical system and finds they emphasize different neurobiological aspects based on their mathematical properties.

This study identifies the rs28834970 variant in PTK2B as a risk factor for Alzheimer's disease, showing it impairs PYK2 function, increases Tau phosphorylation, and alters APP processing in human neuronal cultures.

This study investigates age-related changes in visual short-term memory using fMRI decoding, finding that visual cortex representations weaken with age and load, while frontoparietal regions compensate by strengthening during memory maintenance.

This study examines how alternative host traits affect transient disease dynamics in a two-host system as the alternative host is lost, finding nonmonotonic effects under certain conditions.

This study examines how duplicated genes evolve spatial expression patterns after a genome triplication event in tomato, finding that ancestral expression states are often retained, with some experiencing expression gain or loss linked to fruit quality.

The paper describes CyranoPS, a temperate corynephage infecting Corynebacterium glutamicum, and reports its genome structure, infection mechanisms, and lysogeny regulation.

This study identifies Gpr149 as an endogenous antigen in SB28 glioblastoma that can be targeted by vaccination to induce protective immunity against checkpoint inhibitor-refractory tumors.

iGEX provides an interactive platform for exploring transcriptomic and proteomic datasets, enabling comparison of expression patterns across experiments and public resources.

The paper uses an interpretable deep learning model to classify lung tissue as normal or cancerous by combining fluorophore concentration and entropy features, achieving high accuracy.

This study defines the core proteome and contaminants of plasma extracellular vesicles through a meta-analysis of 515 human proteomes, revealing distinct biological sources and functional modules.

This study examines how fructose-responsive gene regulation varies across intestinal regions in mice and fruit flies, finding conserved pathways and divergent metabolic responses.

The paper identifies a second-sphere threonine residue that directs iron-oxygen species in an Fe(II)/α-ketoglutarate-dependent isonitrile synthase, revealing its role in catalytic regulation.

The paper examines how landscape features, climate, and land use affect sand fly communities in central Panama, finding that grassland cover and fragmentation metrics significantly influence species occurrence and abundance.

This paper identifies mSUPYNL1 as a retrovirus-derived protein that suppresses membrane fusion through direct recognition of envelope glycoproteins, distinct from receptor interference mechanisms.

This paper uses AlphaFold 3 to predict T cell receptor antigen specificity from sequence, achieving high accuracy on unseen epitopes.

This paper demonstrates that a genomic language model can generate functional regulatory DNA sequences using few examples, showing improved performance in cell-type-specific gene expression and neuronal labeling.

This study shows that reducing neuroligin 3 in Drosophila extends lifespan and alters social behavior, linking synaptic function to longevity.

The paper uses scRNA-seq to compare IL-13-treated esophageal organoids with EoE biopsies, revealing shared cell state heterogeneity and differentiation hierarchy dysregulation.

This study examines how urbanisation affects foraging behavior and social interactions in palm squirrels, finding that urban squirrels show stronger approach tendencies and increased exploration due to higher competition.

The paper validates an LC-MS/MS method to quantify kynurenine pathway metabolites and ratios in brain tissue and microglial supernatant, showing altered ratios after neonatal stroke.