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This paper designs protein assemblies that switch between structural states using engineered interfaces, demonstrating temperature-responsive transitions from capsids to 2D arrays.

The paper introduces a human stem cell-based model of the nigrostriatal pathway that mimics in vivo connectivity and reveals target-dependent dopamine neuron maturation.

This study analyzes the genetic diversity and population structure of Fusarium graminearum from wheat grains and maize residues to understand inoculum dispersal patterns in wheat fields.

The paper identifies human antibodies against a mosquito salivary protein, SG1L3, that binds to Plasmodium falciparum sporozoites but does not block infection.

The paper analyzes a citizen science dataset to show that UK farmland bird species richness is higher on farms with gamebird shoots compared to similar farms without shoots.

The paper develops three far-red fluorescent antagonists as BRET tracers for D2R, enabling quantitative ligand binding measurements at recombinant and endogenous receptors.

This study identifies new photobiocatalytic C-C couplings by combining PLP enzymes with photocatalysts, enabling the synthesis of non-canonical amino acids through directed evolution.

This paper develops a minimal mathematical model to predict treatment-free remission in chronic myeloid leukemia using leukemic fitness, and proposes adaptive therapy strategies based on this parameter.

The paper develops a multiplex CRISPR-Cas9 gRNA toolkit to generate fully unpigmented zebrafish larvae with minimal mortality, enabling improved imaging without chemical inhibitors.

The paper identifies differences in synaptic nanoarchitectures between prefrontal and somatosensory cortices, linking loose coupling to higher order brain functions.

The paper finds that early pregnancy SARS2 vaccination is associated with increased detection of T cell maternal microchimerism in cord blood.

This study presents a chromosome-scale genome assembly of Edelweiss, revealing its recent allotetraploid origin and localized subgenome dominance.

The paper uses long-read sequencing to analyze telomere inheritance patterns in human trios, finding parent-of-origin effects and heritable influences on telomere length.

This study identifies PNPLA2, GOT1, and GPX4 as ferroptosis-suppressors whose loss accelerates breast cancer recurrence by promoting dormancy exit and enhancing ferroptosis resistance in dormant cells.

The paper identifies two rodent-specific transposable element subfamilies that function as cell-type-specific enhancers in the mouse immune system, contributing to cell identity and gene regulation.

This study identifies potential neurodegeneration targets of sulforaphane using computational methods across multiple datasets.

This study uses neural field models to assess thalamocortical function in disorders of consciousness, finding reduced corticothalamic integrity in UWS compared to MCS.

This study shows that hepatic stellate cells enhance HCC proliferation through HIF-dependent metabolic changes and H2O2 signaling.

This study evaluates Cas9 fusion proteins in Drosophila to enhance homing gene drive performance by improving HDR and reducing resistance.