Cancer BiologybioRxivPreprint
Loss of Ferroptosis-suppressors Accelerates Breast Cancer Recurrence by Promoting Dormancy Exit
Emily K. Shea, Matthew Lawrence-Paul, Amulya Sreekumar…·Lewis A. Chodosh
This study identifies PNPLA2, GOT1, and GPX4 as ferroptosis-suppressors whose loss accelerates breast cancer recurrence by promoting dormancy exit and enhancing ferroptosis resistance in dormant cells.