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This study identifies HRG as a plasma biomarker of Ni-Cr exposure and reveals nuclear toxicity linked to DNA damage and epigenetic disruption in house sparrows.

This study links HIV reservoir size to biological aging and non-AIDS comorbidities in people on suppressive antiretroviral therapy, independent of inflammation and immune history.

The paper maps gene expression, chromatin accessibility, and DNA methylation in developing human brain cells to understand regulatory interactions and their role in disease.

The paper examines the structural relationships between SLC12 cotransporter C-terminal domains, universal stress proteins, and adenylating enzymes, identifying potential sites for protein adenylation.

This study uses a Drosophila model to identify PRKX as a potential therapeutic target in bladder cancer by combining genotype-informed screening with human cell line validation.

This study shows that Synaptotagmin 7 regulates synaptic vesicle trafficking differently at tonic and phasic synapses in Drosophila.

The paper identifies a small ORF that regulates flagellar gene expression and virulence by modulating RNA structure in Salmonella and related bacteria.

This study examines transcriptional and DNA methylation changes in the hippocampus and prefrontal cortex of irradiated mice, identifying cell-type-specific gene expression and methylation patterns linked to cognitive deficits.

This study generates a transcriptomic atlas of Bostrychia moritziana to investigate the regulatory architecture and evolution of its triphasic life cycle, revealing modular gene regulation and evolutionary integration of developmental programs.

This study uses saturation barcoding and ultra-long-read sequencing to resolve the structure and variation of human nucleolar organizer regions (NORs) in the K562 cell line.

The paper tests the 'anvil effect' hypothesis by showing that surface-adherent bacteria are preferentially lysed during mechanical extraction, leading to DNA yield bias.

PAMP translates turnover predictions into specific enzyme mutations, achieving high positive candidate rates and cumulative gains through gradient-guided projection.

This study shows Rab27a modulation improves neutrophil function in hemorrhage patients facing secondary respiratory infections by enhancing recruitment and antimicrobial activity.

This study shows avian reovirus induces ferroptosis and modulates lipid metabolism in infected cells, leading to lipid droplet formation and syncytium formation.

This study compares two neural circuits to show that a feed-forward layer improves learning and stabilizes attractor states by altering geometric properties of population activity.

The paper uses ocean current models to predict genomic diversity patterns in coastal species, finding that lineage source regions (LSRs) better explain genetic structure than isolation-by-distance.

This study shows that combining PD-1 blockade and HER2-targeted therapy in gastric cancer reduces EMT and extracellular matrix remodelling while enhancing cytotoxic immune signatures.

This study investigates Mincle's role in exacerbated apical periodontitis in a cherubism mouse model, finding that Mincle has dual functions in inflammation and resolution, with fine-tuned suppression reducing bone loss.

This study uses fNIRS to estimate hearing thresholds in sleeping infants by modeling the relationship between auditory stimuli and cortical hemodynamic responses.

The paper analyzes peptide-level evidence from proteomics datasets and finds a depletion of basic peptides in detected evidence compared to theoretical tryptic peptides.