ImmunologyThe EMBO JournalPeer-reviewed
The transcription factor IRF-5 is essential for the metabolic rewiring of CD8 T cells during chronic infection
Linh Thuy Mai, Sharada Swaminathan, Trieu Hai Nguyen…·Simona Stäger
This study identifies IRF-5 as essential for maintaining mitochondrial function and oxidative phosphorylation in CD8 T cells during chronic LCMV Cl13 infection, preventing functional exhaustion and cell death.
8 citations