Simona Stäger

This study shows that HIV-1 infected cells with open Env conformations are vulnerable to ADCP mediated by PWH plasma, and that Nef and Vpu protect against this by preventing premature Env opening.

This study identifies IRF-5 as essential for maintaining mitochondrial function and oxidative phosphorylation in CD8 T cells during chronic LCMV Cl13 infection, preventing functional exhaustion and cell death.