Author

A. A. Desai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

P. M. Tessier· 2 shared A. Asnani· 1 shared A. Diab· 1 shared A. Diwan· 1 shared A. Girardi· 1 shared A. Javaheri· 1 shared A. Kovacs· 1 shared A. Picataggi· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

P. M. Tessier

Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivDec 11, 2023

Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily

H. S. Jhajj, J. S. Schardt, N. Khalasawi…·P. M. Tessier

This paper describes a method to generate biepitopic antibodies that activate TNF receptors by combining single-chain antibodies with IgG light chains, enhancing agonist activity without animal immunization.

DOI 10.1016/j.chembiol.2024.03.010

humanproteomics

BioengineeringbioRxivPreprintJul 4, 2023

Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils

A. A. Desai, J. M. Zupancic, H. Trzeciakiewicz…·P. M. Tessier

This paper describes a FACS method using quantum dots to isolate high-quality conformational antibodies against insoluble antigens like amyloid fibrils.

DOI 10.1101/2023.07.04.547698

humanflow cytometry

Pharmacology & ToxicologybioRxivJan 12, 2021

Apolipoprotein M attenuates anthracycline cardiotoxicity and lysosomal injury

Z. Guo, C. Valenzuela Ripoll, A. Picataggi…·A. Javaheri

This paper investigates the role of apolipoprotein M in anthracycline cardiotoxicity, finding that ApoM protects against cardiac dysfunction and lysosomal injury through the autophagy-lysosome pathway.

DOI 10.1016/j.jacbts.2022.09.010

mouseproteomics