Spermidine dampens inflammation by directly inhibiting Th17 cytokine production through a PRDX1 associated antioxidant pathway
J. Luo, Y. J. Kim, X. An, L. Fan, C. Erb, D. Lou, Y. Yao, A. A. Ferguson, Y. Pan, K. Chen
This study shows spermidine directly inhibits Th17 cytokine production via PRDX1-dependent antioxidant activity, reducing lung inflammation in mouse models.
bioRxiv · Aug 31, 2021Immunology