Cancer BiologybioRxiv
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
K. Thombare, R. Vaid, P. Pucci…·T. Mondal
This study shows METTL3 and MYCN cooperate to maintain undifferentiated neural crest cells in neuroblastoma, and METTL3 inhibition promotes differentiation and chemosensitivity.
DOI 10.1038/s44318-024-00299-8