Author

A. A. Ruberto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Vantaux· 2 shared S. P. Maher· 2 shared A. Grechez-Cassiau· 1 shared A. Harupa-Chung· 1 shared A. Jex· 1 shared A. K. Chatterjee· 1 shared A. Orban· 1 shared A. T. Chao· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. Vantaux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

S. P. Maher, M. A. Bakowski, A. Vantaux, E. L. Flannery, C. Andolina, M. Gupta, Y. Antonova-Koch, M. Argomaniz, C.-M. Monica, C. Brice, A. T. Chao, A. K. Chatterjee, W. T. Cheng, E. Chuenchob, C. A. Cooper, , McNama

The paper identifies epigenetic inhibitors active against Plasmodium vivax hypnozoites through drug repurposing screens, showing epigenetic pathways are critical for hypnozoite quiescence.

bioRxiv · Jan 31, 2023 · PreprintCell Biology

Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

A. A. Ruberto, S. P. Maher, A. Vantaux, C. J. Joyner, C. Bourke, B. Balan, A. Jex, I. Mueller, B. Witkowski, D. E. Kyle

This study uses single-cell RNA sequencing to analyze P. vivax-infected hepatocytes, identifying transcriptomic differences between schizonts and hypnozoites and potential therapeutic targets.

bioRxiv · Feb 1, 2022Microbiology

KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

A. A. Ruberto, A. Grechez-Cassiau, S. Guerin, L. Martin, J. S. Revel, M. Mehiri, M. Subramaniam, F. Delaunay, M. Teboul

This study shows that KLF10 integrates circadian timing and sugar signaling in the liver to regulate metabolism and prevent glucose intolerance and hepatic steatosis.

bioRxiv · Dec 22, 2020Cell Biology