CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo
L. M. Vuong, S. J. Hachey, J. Shiu, D. F. Xie, N. Salvador, N. Brindani, S. M. Bertozzi, M. Summa, R. Bertorelli, A. Armirotti, R. Pham, V. S. Ku, T. Nguyen, B. Choi, C. C. Hughes, , A. K. Ganesan
This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.
bioRxiv · Apr 9, 2024 · PreprintCancer Biology