B. Choi

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.

A large-scale bioinformatic study of graspimiditides and structural characterization of albusimiditide

This paper identifies and classifies graspimiditides, a subclass of graspetides with aspartimide modifications, and characterizes the structure of albusimiditide.

Semi-automated protocol to quantify and characterize fluorescent three-dimensional vascular images

The paper describes a semi-automated protocol to quantify and characterize 3D vascular images in mouse tissues, achieving 80% sensitivity and 90% specificity in automated segmentation.

Clinical and immunological signatures of severe COVID-19 in previously healthy patients with clonal hematopoiesis

This study identifies clonal hematopoiesis as an independent risk factor for severe COVID-19 in previously healthy patients, revealing distinct immunological and epigenetic signatures.

Fuscimiditide: a RiPP with {Omega}-Ester and Aspartimide Post-translational Modifications

This paper describes the discovery of a new family of omega-ester linked peptides, fuscimiditide, and characterizes its post-translational modifications and biosynthesis.

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

The paper identifies an immunosuppressive microenvironment in human prostate cancer bone metastases and shows that disrupting the CCL20-CCR6 axis can restore T cell reactivity and improve survival in mice.

Impact of Chronic Total Occlusion Lesion Length onSix-month Angiographic and 2-year Clinical Outcomes

This study compares 6-month angiographic and 2-year clinical outcomes between long and short chronic total occlusion (CTO) lesions after successful DES PCI, finding higher repeat PCI rates in long CTO lesions.