Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
R. H. F. Bender, B. T. O'Donnell, B. Shergill…·C. C. Hughes
This paper develops a vascularized 3D model of human pancreatic islets to study immune cell interactions and islet destruction in diabetes.
S. J. Hachey, C. J. Hatch, D. Gaebler…·C. C. Hughes
The paper uses a vascularized micro-tumor model to identify therapeutic targets in TNBC stromal interactions, showing efficacy of Tie2 and Her3/Akt inhibition.
K. V. Nguyen Ngoc, S. Sai, Y. Jun…·M. Sander
This study shows that engineered vasculature enhances the function of stem cell-derived islet organoids by improving calcium influx and insulin secretion in beta-cells.
S. J. Hachey, S. Movsesyan, Q. H. Nguyen…·C. C. Hughes
This paper validates a vascularized micro-tumor model for colorectal cancer that better replicates in vivo drug responses than traditional 2D or 3D models.