TRAF6-IRF5 kinetics, TRIF, and biophysical factors drive synergistic innate responses to particle-mediated MPLA-CpG co-presentation
P. Pradhan, R. Toy, N. Jhita, E. L. Blanchard, A. Atalis, B. Pandey, P. J. Santangelo, D. M. Shayakhmetov, K. Roy
This study identifies TRAF6-IRF5 kinetics and TRIF signaling as key drivers of synergistic innate immune responses to MPLA-CpG co-presentation in BM-APCs.
bioRxiv · Jul 17, 2020Immunology