S. Nandi

Ready, set, yellow! Color Preference of Indian Free-ranging Dogs

This study investigates color preference in Indian free-ranging dogs, finding a strong preference for yellow over blue and gray, and yellow over food rewards.

Anti-Biofilm Potential of Nanonized Eugenol against Pseudomonas aeruginosa

This study develops eugenol nanoparticles (ENPs) that show enhanced anti-biofilm activity against Pseudomonas aeruginosa compared to bulk eugenol.

Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India

This study evaluates a new live-attenuated LSD vaccine, showing it is safe, immunogenic, and effective in protecting cattle against LSD with high seroconversion rates.

Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties

This study identifies planar polarized actomyosin cables as essential for coordinating cell dynamics and positioning during Drosophila germband retraction.

Whole-Genome Sequence of African Swine Fever Virus isolate from India provides insights into diversity and evolution

The paper reports the whole-genome sequence of an African swine fever virus isolate from India and compares it to other ASFV genomes to study genetic diversity and evolution.

Systemic infection of SARS-CoV-2 in free ranging Leopard (Panthera pardus fusca) in India

The paper reports SARS-CoV-2 infection in a free-ranging Indian leopard, confirming Delta variant infection and highlighting the need for wildlife screening.

Production of novel Spike truncations in Chinese hamster ovary cells

The paper improves Spike protein expression in CHO cells by developing truncations that outperform full-length Spike and RBD in expression levels and antibody binding.

Functionalizing silica sol-gel with entrapped plant virus-based immunosorbent nanoparticles

The paper immobilizes a virus-based nanomaterial in silica sol-gel to create a stable, reusable system for antibody binding and elution in biosensing applications.

50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA

This paper reports the structure of the Mycobacterium tuberculosis TlyA enzyme bound to the 50S ribosomal subunit, revealing mechanisms of rRNA substrate recognition and modification that contribute to antibiotic resistance.

Affinity sedimentation and magnetic separation with plant-made immunosorbent nanoparticles for therapeutic protein purification

This paper develops plant-made immunosorbent nanoparticles for therapeutic protein purification, demonstrating enhanced binding capacity and introducing magnetic separation to improve efficiency.

SARS-Cov-2 Spike binding to ACE2 is stronger and longer ranged due to glycan interaction

The paper uses molecular dynamics simulations to show that glycosylation enhances the binding strength and range of SARS-CoV-2 Spike to ACE2 through glycan-mediated interactions.

Evaluating the cost of pharmaceutical purification for a long-duration space exploration medical foundry

This study evaluates pharmaceutical purification costs for space missions using the ESM metric, comparing biotic and abiotic methods for monoclonal antibody purification.

Analysis of variability of functionals of recombinant protein production trajectories based on limited data

The paper develops a bootstrap-based method to infer variability in functionals of protein production trajectories from limited data, applied to time-to-harvest and maximal productivity.

DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer

This study shows UV-nail polish dryer radiation causes DNA damage and somatic mutations in mammalian cells, with mutagenic patterns linked to reactive oxygen species.

Bioprinting transgenic plant cells for production of a recombinant biodefense agent

The paper demonstrates a bioprinting system using transgenic rice cells to produce recombinant BChE, maintaining viability and production levels comparable to liquid cultures.

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain

The paper develops and simulates fully glycosylated ACE2-Fc fusion proteins and their interaction with SARS-CoV-2 spike protein RBD, showing glycan effects on conformation and optimizing glycosylation modeling algorithms.

Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: A pilot study

This study examines changes in circulating progenitor cells during CPB and finds that reduced early CD34+ and CD34+CD133+ HSC counts predict clinically significant vasoplegia.

Role of a kinesin motor in cancer cell mechanics

This study investigates the role of KIF20A, a kinesin motor protein, in bladder cancer cell mechanics and motility, showing that its inhibition alters intracellular and cortical stiffness.

Absence of receptor guanylyl cyclase C enhances ileal damage and reduces cytokine and antimicrobial peptide production during oral Salmonella Typhimurium infection