G. Schoehn

This study uses cryo-electron tomography to reveal the ultrastructural organization of Bacillus subtilis spores, including the toroidal chromosome and nascent coat layers during sporulation.

This paper develops a vaccine platform using bacteriophage T5 capsid-like particles to display antigens, showing strong immune responses without adjuvants.

This study determines the structure of bacteriophage T5 RBPpb5 bound to its E. coli receptor FhuA, revealing the mechanism of host recognition and infection initiation.

This paper presents the structure of bacteriophage T5 tip and its interaction with E. coli receptor FhuA, revealing conformational changes during infection and cell wall perforation.

This study identifies a novel mechanism by which the F-box protein UFO modulates the DNA-binding specificity of the master transcription factor LFY through direct interaction with novel cis-elements.

This study presents cryo-EM structures of CHMP2A-CHMP3 ESCRT-III filaments and shows they constrict and cleave membrane tubes through electrostatic interactions and VPS4-mediated remodeling.

This study shows how prefoldin inhibits IAPP fibril formation by binding to the N-terminal segment of IAPP on fibril surfaces and ends, reducing aggregate size and number.

This paper describes a vaccine platform using adenovirus-inspired nanoparticles decorated with SARS-CoV-2 RBD to elicit potent neutralizing antibodies in mice.

The paper shows that a triple-mutant of plectasin forms reversible helical non-amyloid fibrils, with high-resolution structure and pH-dependent equilibrium.

This study develops a synthetic SARS-CoV-2 S glycoprotein virus-like particle vaccine that protects macaques from infection through strong antibody and T cell responses.

This study uses cryo-EM to reveal the structural dynamics of La Crosse virus polymerase, elucidating mechanisms of replication and transcription in Peribunyaviridae.

This study examines the immediate and sustained effects of cobalt- and zinc-based pigments on macrophages, revealing functional disorders that persist even at non-toxic doses.

The paper observes oriented attachment in protein crystallization, challenging previous classifications and showing non-classical nucleation mechanisms.

The paper shows DC/L-SIGN receptors on antigen-presenting cells enhance SARS-CoV-2 trans-infection, which can be blocked by a glycomimetic compound.

This study presents the cryo-EM structures of La Crosse virus polymerase in pre-initiation and elongation states, revealing conformational changes important for transcription.

This paper develops a 3D electron microscopy workflow to generate nanometric phytoplankton models and identifies conserved subcellular features related to energy management.

The paper integrates NMR and cryo-EM to determine the atomic structure of a large enzyme complex, achieving high precision and accuracy beyond the limitations of each method individually.

The paper determines the cryo-EM structure of a complex between adenovirus type 3 fibre knob and desmoglein 2, revealing a novel receptor engagement mechanism.