Author

A. Bhide

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Sen· 1 shared A. Venkatesan· 1 shared I. D. Pogozheva· 1 shared J. Adair· 1 shared J. Geng· 1 shared J. Kauffman· 1 shared K. Gentile· 1 shared M. Kandarpa· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Sen

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2 papers

Recent·Most cited

Enzyme Aggregation and Fragmentation Induced by Catalysis Relevant Species

K. Gentile, A. Bhide, J. Kauffman, S. Ghosh, S. Maiti, J. Adair, T.-H. Lee, A. Sen

The paper examines enzyme aggregation and fragmentation during catalysis in three model enzymes, finding that specific substrates and ions induce structural changes without affecting catalytic activity.

bioRxiv · Sep 3, 2021Biophysics

Mpl is activated by dimers of MPN-linked calreticulin mutants stabilized by disulfide bonds and ionic interactions

A. Venkatesan, J. Geng, M. Kandarpa, S. Wijeyesakere, A. Bhide, M. Talpaz, I. D. Pogozheva, M. Raghavan

This study identifies how mutated calreticulin (CRTDel52) forms dimers stabilized by disulfide bonds and ionic interactions, leading to Mpl activation and cytokine-independent cell proliferation in MPNs.

bioRxiv · Sep 13, 2020 · PreprintCancer Biology