Influence of MUC1 on trafficking of TRPV5 and TRPV6 and in vivo Ca2+ homeostasis.
M. M. Al-Bataineh, C. L. Kinlough, A. L. Marciszyn, T. Lam, L. Ye, K. Kidd, J. C. Maggiore, P. A. Poland, A. Bleyer, D. J. Bain, T. R. Kleyman, R. P. Hughey, E. C. Ray
This study investigates how MUC1 affects TRPV5 and TRPV6 trafficking and Ca2+ homeostasis, finding that MUC1 reduces endocytosis of these channels and influences blood Ca2+ levels in mice and humans.
bioRxiv · Oct 22, 2022 · PreprintPhysiology