A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe Syndrome
B. Akhtar, P. Bhatia, S. Acharya, S. Sharma, Y. Sharma, A. BS, A. Vasudevan, R. Padinjat
This study generates human stem cell lines from Lowe Syndrome patients to investigate the cellular and biochemical mechanisms of brain development defects caused by OCRL1 mutations.
bioRxiv · Aug 19, 2021Cell Biology