Author

B. Alvarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Nielsen· 2 shared A. Buschiazzo· 1 shared A. Sette· 1 shared B. Peters· 1 shared C. Barra· 1 shared C. M. Barra· 1 shared F. Carrion· 1 shared F. Olivieri· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

M. Nielsen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome

S. Kaabinejadian, C. Barra, B. Alvarez, H. Yari, W. Hildebrand, M. Nielsen

The paper introduces MHCMotifDecon, a tool for accurately deconvoluting immunopeptidomics data, revealing HLA-DRB3/4/5's significant role in the DR immunopeptidome.

bioRxiv · Nov 23, 2021Immunology

Molecular basis of unidirectional information transmission in two-component systems: lessons from the DesK-DesR thermosensor

S. Lima, J. Blanco, F. Olivieri, J. A. Imelio, F. Carrion, B. Alvarez, A. Buschiazzo, M. Marti, F. Trajtenberg

The paper investigates the DesK-DesR two-component system in Bacillus subtilis, revealing structural and kinetic mechanisms that enable unidirectional signal transmission.

bioRxiv · Nov 12, 2021 · PreprintBiophysics

In vivo diversification of target genomic sites using processive T7 RNA polymerase-base deaminase fusions blocked by RNA-guided dCas9

B. Alvarez, M. Mencia, V. de Lorenzo, L. A. Fernandez

This paper develops an in vivo system to diversify specific DNA segments using T7 RNA polymerase-base deaminase fusions blocked by RNA-guided dCas9, demonstrating efficiency in E. coli.

bioRxiv · Nov 22, 2019 · PreprintBioengineering

Footprints of antigen processing boost MHC class II natural ligand binding predictions

C. M. Barra, B. Alvarez, S. Paul, A. Sette, B. Peters, S. Buus, M. Andreatta, M. Nielsen

This study develops MHC class II ligand binding predictors trained on naturally eluted peptides, showing improved performance by incorporating antigen processing rules.

bioRxiv · Aug 6, 2018Immunology