Author

A. Chalkias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. d'Aloja· 2 shared E. Locci· 2 shared J. Liu· 2 shared M. H. Scheetz· 2 shared N. Rhodes· 2 shared T. Xanthos· 2 shared A. Chighine· 1 shared A. Gilchrist· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPharmacology & Toxicology

E. d'Aloja

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2 papers

Recent·Most cited

Urinary Metabolomics from a Dose-Fractionated Polymyxin B Rat Model of Acute Kidney Injury

E. Locci, J. Liu, G. Pais, A. Chighine, D. A. Kahnamoei, T. Xanthos, A. Chalkias, A. Lee, A. Hauser, J. Chang, N. Rhodes, E. d'Aloja, M. H. Scheetz

This study uses urinary metabolomics in a rat model to show that taurine levels increase on day 1 of polymyxin B treatment and correlate with kidney injury markers.

bioRxiv · May 21, 2021Pharmacology & Toxicology

Urinary biomarker and histopathological evaluation of vancomycin and piperacillin-tazobactam nephrotoxicity in comparison with vancomycin in a rat model and a confirmatory cellular model

G. M. Pais, J. Liu, S. N. Avedissian, T. Xanthos, A. Chalkias, E. d'Aloja, E. Locci, A. Gilchrist, W. C. Prozialeck, N. Rhodes, T. P. Lodise, J. C. Fitzgerald, K. Downes, A. Zuppa, M. H. Scheetz

This study evaluates kidney injury from vancomycin and piperacillin-tazobactam in rats and cells, finding no increased toxicity from the combination compared to vancomycin alone.

Journal of Antimicrobial Chemotherapy · Feb 3, 2020Peer-reviewedPharmacology & Toxicology