Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis
R. Herlo, J. H. Schmidt, J. Rombach, A. H. Larsen, M. Stoklund, M. Perslev, T. T. E. Nielsen, K. A. Andersen, C. Herenbrink, M. D. Lycas, A. Ejdrup, N. Christensen, J. P. Christensen, M. Salman, F. Herborg, , k. L. Madsen
The paper identifies amphipathic helix 8 as a driver of constitutive GPCR endocytosis through membrane curvature association.
bioRxiv · Mar 27, 2024Cell Biology