Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
A. Papadas, G. Deb, A. Officer, A. Cicala, C. Hope, P. Emmerich, J. Wiesner, A. Pagenkopf, G. Arauz, V. Bansal, K. Matkowskyj, D. A. Deming, K. Politi, S. Abrams, O. Harismendy, F. Asimakopoulos
The paper shows that stromal remodeling generates signals that regulate dendritic cell survival and activity, enhancing T-cell inflammation in the tumor microenvironment.
bioRxiv · Nov 10, 2021Immunology