O. Harismendy

This study identifies immune microenvironment features and myoepithelial continuity as key determinants of progression in high-risk DCIS.

This study integrates genomic and transcriptomic analysis of intraductal papillary mucinous neoplasms (IPMNs) to identify molecular features associated with progression to high-grade lesions and cancer.

This study identifies changes in stromal-epithelial interactions between in situ and invasive breast cancer using gene expression profiling, finding significant ligand-receptor pairs associated with prognosis.

The paper shows that stromal remodeling generates signals that regulate dendritic cell survival and activity, enhancing T-cell inflammation in the tumor microenvironment.

The paper identifies germline variants associated with the tumor immune microenvironment, linking them to cancer risk and immunotherapy response.

The paper characterizes the step-wise acquisition of carboplatin resistance in ovarian cancer using single-cell gene expression analysis and identifies distinct transcriptional patterns associated with resistance.