Author

A. D. Ebert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. S. O'Brien· 2 shared R. L. Mokry· 2 shared S. S. Terhune· 2 shared A. C. Raimer· 1 shared A. G. Matera· 1 shared A. I. Lamond· 1 shared A. M. Spring· 1 shared C. L. Lorson· 1 shared

Activity by Year

2016-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. S. O'Brien

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nitric Oxide Attenuates Human Cytomegalovirus Infection yet Disrupts Neural Cell Differentiation and Tissue Organization

R. L. Mokry, B. S. O'Brien, J. W. Adelman, S. Rosas, A. D. Ebert, S. S. Terhune

This study shows nitric oxide inhibits HCMV infection but causes neural differentiation defects and tissue disorganization in cortical organoids.

bioRxiv · Nov 9, 2021Microbiology

Downregulation of Neurodevelopmental Gene Expression in iPSC-Derived Cerebral Organoids Upon Infection by Human Cytomegalovirus

B. S. O'Brien, R. L. Mokry, M. L. Schumacher, K. Pulakanti, S. Rao, S. S. Terhune, A. D. Ebert

This study shows HCMV infection reduces neurodevelopmental gene expression in cerebral organoids, even when IE proteins are disrupted, suggesting alternative viral mechanisms drive the effect.

bioRxiv · Aug 1, 2021Cell Biology

Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCFSlmb degron

K. M. Gray, K. A. Kaifer, D. Baillat, Y. Wen, T. R. Bonacci, A. D. Ebert, A. C. Raimer, A. M. Spring, S. ten Have, J. J. Glascock, K. Gupta, G. D. Van Duyne, M. J. Emanuele, A. I. Lamond, E. J. Wagner, , A. G. Matera

The paper identifies SCFSlmb as a regulator of SMN protein stability through a degron, showing that self-oligomerization stabilizes SMN isoforms and mitigates SMA severity.

bioRxiv · Sep 30, 2016Biochemistry