Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE
J. Chongsaritsinsuk, A. D. Steigmeyer, K. E. Mahoney, M. A. Rosenfeld, T. M. Lucas, D. Ince, F. L. Kearns, A. S. Battison, M. A. Hollenhorst, J. Shon, K. H. Tiemeyer, V. Attah, C. Kwon, C. R. Bertozzi, M. J. Ferracane, , S. A. Malaker
The paper uses a mucinase to analyze glycoproteomic features of TIM family proteins and shows how glycosylation affects their structure through molecular dynamics simulations.
bioRxiv · Feb 1, 2023Cancer Biology