ImmunologybioRxivPreprint
GATA2 Induces a Stem Cell-Like Transcriptional Program in Macrophages that Promotes Atherogenesis.
Amena Aktar, Angela M. Vrieze, Kiera Telesnicki…·Bryan Heit
This study shows that GATA2 upregulation in macrophages promotes atherogenesis by inducing a stem cell-like transcriptional program that impairs cholesterol efflux and phagocytosis.
DOI 10.1101/2025.07.18.665581