Author

Rodney P. DeKoter

Western UniversityORCID 0000-0002-9201-1983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Research Focus:variant calling· 2

Frequent Co-Authors

Allanna C. E. MacKenzie· 2 shared Carolina R. Batista· 2 shared James Iansavitchous· 2 shared Mia P. SamsiD· 2 shared Michelle Lim· 2 shared A. Dave Nagpal· 1 shared Amena Aktar· 1 shared Angela M. Vrieze· 1 shared

Activity by Year

2018-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

Allanna C. E. MacKenzie

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 18, 2025

GATA2 Induces a Stem Cell-Like Transcriptional Program in Macrophages that Promotes Atherogenesis.

Amena Aktar, Angela M. Vrieze, Kiera Telesnicki…·Bryan Heit

This study shows that GATA2 upregulation in macrophages promotes atherogenesis by inducing a stem cell-like transcriptional program that impairs cholesterol efflux and phagocytosis.

DOI 10.1101/2025.07.18.665581

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintDec 19, 2024

T505A variant of ETV5 promotes proliferation of precursor B cells in a mouse model of acute lymphoblastic leukemia

Joshua Yi, Michael P. Wu, Michaela L. Dowling…·Rodney P. DeKoter

DOI 10.1101/2024.12.19.629436

mousewhole-exome sequencing

𝕏 PostBluesky

ImmunologyMolecular ImmunologyPeer-reviewedSep 26, 2024

Negative regulation of Activation-Induced Cytidine Deaminase gene transcription in developing B cells by a PU.1-interacting intronic region

Allanna C. E. MacKenzie, Mia P. Sams, Jane H.-C. Lin…·Rodney P. DeKoter

The paper identifies a PU.1-interacting intronic region that negatively regulates Aicda transcription in developing B cells.

DOI 10.1016/j.molimm.2024.09.010

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologyJournal of Pharmacology and Experimental TherapeuticsPeer-reviewedFeb 9, 2024

N-Acetylcysteine alters disease progression and increases Janus Kinase mutation frequency in a mouse model of precursor B cell acute lymphoblastic leukemia

Mia P. Sams, James Iansavitchous, Madeline Astridge…·Rodney P. DeKoter

This study shows that N-acetylcysteine (NAC) alters disease progression in a mouse model of B-ALL by increasing Jak3 R653H mutation frequency.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 2, 2018

Deletion of genes encoding PU.1 and Spi-B leads to B cell acute lymphoblastic leukemia associated with driver mutations in Janus Kinases

Carolina R. Batista, Michelle Lim, Anne-Sophie Laramée…·Rodney P. DeKoter

This study shows that deletion of PU.1 and Spi-B in mice leads to B-ALL with JAK mutations as secondary drivers.

DOI 10.1101/291054

mousebulk RNA-seq

𝕏 PostBluesky