SARS-CoV-2 entry route impacts a range of downstream viral and cellular processes
B. Qu, C. Miskey, A. Goemer, D. Potmus, M. Nocke, R. D. V. Kleinert, T. K. Itotia, L. Valder, J. Brueckmann, S. Hoeck, F. D. Hastert, C. von Rhein, C. Schuermann, A. Ebenig, M. Widera, , R. J. P. Brown
This study shows that SARS-CoV-2 entry via TMPRSS2 or endolysosomal cathepsins affects viral replication, immune response, and genome evolution.
bioRxiv · Aug 5, 2022 · PreprintMicrobiology