CAR/Nr1i3 directs T cell adaptation to bile acids in the small intestine
M. L. Chen, X. Huang, H. Wang, Y. Liu, J. Shang, A. Eliason, C. Hegner, H. Park, B. Frey, G. Wang, D. J. Kojetin, C. T. Weaver, M. E. Pipkin, D. D. Moore, M. S. Sundrud
This study identifies CAR/Nr1i3 as a regulator of T cell adaptation to bile acids in the small intestine, showing its role in detoxification and inflammation resolution.
bioRxiv · Jul 30, 2020 · PreprintImmunology