Author

M. E. Pipkin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. J. Getzler· 2 shared C. Toma· 2 shared G. J. Martinez· 2 shared H. Diao· 2 shared J. J. Milner· 2 shared J. Kim· 2 shared M. A. Frederick· 2 shared S. Crotty· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. J. Getzler

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Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 18, 2023

Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8+ T stem cell memory

A. J. Getzler, M. A. Frederick, J. J. Milner…·M. E. Pipkin

This study identifies Mll1 as a key factor in establishing CD8+ T stem cell memory by promoting H3K4me3 deposition and regulating Pol II elongation during TCR stimulation.

DOI 10.1101/2023.01.18.524461

mouseChIP-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 3, 2022

Polycomb Repressive Complex 1 subunit Cbx4 positively regulates effector responses in CD8 T cells

G. A. Melo, T. Xu, C. Caloba…·R. M. Pereira

This study shows that Cbx4 promotes effector CD8 T cell differentiation through SUMOylation and chromodomain mechanisms, impacting memory cell formation during viral infection.

DOI 10.1101/2022.10.03.510675

mouseChIP-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 11, 2021

Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny

H. Diao, R. Chen, S. M. Tsuda…·M. E. Pipkin

The paper defines single-cell trajectories and identifies chromatin regulators that establish antiviral CD8 T cell heterogeneity during acute and chronic infections.

DOI 10.1101/2021.08.11.456014

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 30, 2020

CAR/Nr1i3 directs T cell adaptation to bile acids in the small intestine

M. L. Chen, X. Huang, H. Wang…·M. S. Sundrud

This study identifies CAR/Nr1i3 as a regulator of T cell adaptation to bile acids in the small intestine, showing its role in detoxification and inflammation resolution.

DOI 10.1101/2020.07.30.229864

mousebulk RNA-seq

𝕏 PostBluesky