Author

A. Farfel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

G. D. Luker· 3 shared K. E. Luker· 2 shared P. Ghosh· 2 shared S. Sinha· 2 shared A. F. Brooks· 1 shared B. A. Parker· 1 shared B. Callow· 1 shared B. L. Viglianti· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

G. D. Luker

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Author profile →

3 papers

Recent·Most cited

Predicting efficacy of immunotherapy in mice with triple negative breast cancer using a cholesterol PET radiotracer

N. G. Ciavattone, J. Guan, A. Farfel, T. Desmond, B. L. Viglianti, P. J. Scott, A. F. Brooks, G. D. Luker

The paper uses a cholesterol PET radiotracer to predict immunotherapy response in TNBC mouse models by measuring T cell cholesterol uptake.

bioRxiv · Oct 2, 2023 · PreprintImmunology

A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels

S. Sinha, B. Callow, A. Farfel, S. Roy, S. Chen, S. Rajendran, J. Buschhaus, K. E. Luker, P. Ghosh, G. D. Luker

This study identifies GIV as a key protein transferred from mesenchymal stromal cells to ER+ breast cancer cells via tunnelling nanotubes, driving aggressive tumor phenotypes.

bioRxiv · Mar 18, 2023Cancer Biology

Growth Signaling Autonomy in Circulating Tumor Cells Aids Metastatic Seeding

S. Sinha, A. Farfel, K. E. Luker, B. A. Parker, K. Yeung, G. D. Luker, P. Ghosh

This study defines the transcriptome, proteome, and phenome of growth signaling autonomy in breast cancer cells and shows its role in metastatic progression and drug resistance.

bioRxiv · Dec 2, 2022Cancer Biology