Intermediate antiparallel beta structure in amyloid plaques revealed by infrared spectroscopic imaging
B. Holcombe, A. Foes, S. Banerjee, K. Yeh, S.-H. J. Wang, R. Bhargava, A. Ghosh
The paper uses infrared spectroscopic imaging to show that amyloid plaques in Alzheimer's disease contain antiparallel beta-sheet structures, linking in vitro findings to in vivo pathology.
bioRxiv · Apr 18, 2023 · PreprintBiophysics