Author

B. Holcombe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:imaging· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Foes· 2 shared A. Ghosh· 2 shared S. Banerjee· 2 shared K. Yeh· 1 shared R. Bhargava· 1 shared S. Ringold· 1 shared S.-H. J. Wang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. Foes

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intermediate antiparallel beta structure in amyloid plaques revealed by infrared spectroscopic imaging

B. Holcombe, A. Foes, S. Banerjee, K. Yeh, S.-H. J. Wang, R. Bhargava, A. Ghosh

The paper uses infrared spectroscopic imaging to show that amyloid plaques in Alzheimer's disease contain antiparallel beta-sheet structures, linking in vitro findings to in vivo pathology.

bioRxiv · Apr 18, 2023 · PreprintBiophysics

Structural heterogeneity of amyloid aggregates identified by spatially resolved nanoscale infrared spectroscopy

S. Banerjee, B. Holcombe, S. Ringold, A. Foes, A. Ghosh

This study uses AFM-IR to show structural heterogeneity in amyloid aggregates, revealing that fibrils can have structurally different domains and that early-stage aggregates exhibit varied conformations.

bioRxiv · May 7, 2022 · PreprintBiophysics