S. Luquet

Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity

This study shows that striatal astrocytes regulate behavioral flexibility and metabolism in obesity through chemogenetic manipulation in mice.

CaMK1D signaling in AgRP neurons promotes ghrelin-mediated food intake

This paper identifies CaMK1D as a key mediator of ghrelin-induced food intake in AgRP neurons, showing its role in promoting orexigenic neuropeptide expression and obesity resistance.

The GhsrQ343X allele favors the storage of fat by acting on nutrient partitioning

This study shows that the GhsrQ343X allele alters nutrient partitioning by favoring fat storage, as evidenced by changes in energy metabolism and behavior in mutant rats.

Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity

This study identifies Hacd1 as a regulator of mitochondrial membrane composition in muscle, showing that reduced mitochondrial coupling protects against obesity.

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan.

This study shows that Dlx5 and Dlx6 in GABAergic neurons affect behavior, metabolism, aging, and lifespan in mice.

Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar

The paper shows that short-term sucralose consumption with carbohydrate impairs glucose metabolism and reduces central sensitivity to sweet taste in humans and mice.