CaMKII activity spreads by inter-holoenzyme phosphorylation
I. Lucic, L. Heluin, P.-L. Jiang, A. G. Castro Scalise, C. Wang, A. Franz, M. Wahl, F. Liu, A. J. R. Plested
This study identifies inter-holoenzyme phosphorylation as the mechanism for spreading CaMKII activity, challenging the subunit exchange hypothesis.
bioRxiv · Aug 3, 2022Biophysics